Quantitative analysis of cordycepin in Cordyceps militaris under different extraction methods
نویسندگان
چکیده
منابع مشابه
Development of High Cordycepin-Producing Cordyceps militaris Strains
Cordyceps militaris, known as Dong-Chong-Xia-Cao, produces the most cordycepin among Cordyceps species and can be cultured artificially. For these reasons, C. militaris is widely used as herb or functional food in the East Asia. In this study, we developed a new strain of C. militaris that produces higher cordycepin content than parent strains through mating-based sexual reproduction. Twenty pa...
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Cordycepin, a nucleoside derivative, is an active component of parasitic fungus, Cordyceps militaris which has been known for many pharmacological activities. The present study was carried out to develop an extraction strategy for cordycepin and to evaluate its antimicrobial potential. Solventsolvent extraction method was used to extract cordycepin from liquid culture of C. militaris. Crude con...
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This study reports on the optimization of the extraction conditions of cordycepin from Cordyceps militaris by using ultrasonication. For this purpose, the orthogonal experimental design was used to investigate the effects of factors on the ultrasonic-assisted extraction (UAE). Four factors: extraction time (min), ethanol concentration (%), extraction temperature (°C) and extraction frequency (k...
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Pigmentation of ascospore-derived isolates from seven different natural specimens of Cordyceps militaris EFCC C-5888, EFCC C-7159, EFCC C-7833, EFCC C-7991, EFCC C-8021, EFCC C-8023 and EFCC C-8179 was observed on the plates of Sabouraud Dextrose agar plus Yeast Extract at 25℃ under continuous illumination (500 lux). Pigmentation of the wild-type isolates of C. militaris was diverse ranging fro...
متن کاملCordycepin, a Characteristic Bioactive Constituent in Cordyceps militaris, Ameliorates Hyperuricemia through URAT1 in Hyperuricemic Mice
Recently, we've reported the anti-hyperuricemic effects of Cordyceps militaris. As a characteristic compound of C. militaris, we hypothesized that cordycepin may play a role in preventing hyperurecimia. Remarkably, cordycepin produced important anti-hyperuricemic actions, decreasing SUA (serum uric acid) to 216, 210, and 203 μmol/L (P < 0.01) at 15, 30, and 60 mg/kg in comparison of hyperuricem...
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ژورنال
عنوان ژورنال: Journal of Applied Biological Chemistry
سال: 2021
ISSN: 1976-0442,2234-7941
DOI: 10.3839/jabc.2021.022